Journal Club

A resource for the smart QC microbiologist

MinION portable sequencer from Oxford Nanopore Technologies

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Sterility testing in 5 hours not 14 days

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Neogen Webinar on LAMP Technology in Food Safety Testing

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understanding gluten

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This site is a B2B information site for professional use - clinical diagnostics products listed are for Research Use Only unless otherwise stated.

Journal Club

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Journal Club - 28 May to 8 June

Journal Club

Antibiotic Sensitivity Leptospira Microbiome

09 Jun 2026 Lora Benoit Ph.D

Latest from our Journal Club: a genomic analysis of a canine leptospirosis outbreak in Los Angeles County in 2021, how the microbiome degrades a sweetener with potential to damage intestinal barrier function, and a new AI framework for antimicrobial susceptibility testing (AST).
Clinical & Veterinary Microbiome Assay Development

New AI Framework for Antimicrobial Susceptibility Testing (AST)

New AI framework for AST analysis

Antibiotic Sensitivity

08 Jun 2026 Lora Benoit Ph.D

Researchers developed a deep learning–based image analysis framework capable of automatically interpreting antimicrobial susceptibility testing (AST) results from agar diffusion assays.
Clinical & Veterinary Assay Development

Microbiome Degrades Sweetener with Potential to Damage Intestinal Barrier Function

Common sweetener can be metabolized by gut microbiome with implications for gut

Microbiome

08 Jun 2026 Lora Benoit Ph.D

A dynamic in vitro gut simulator inoculated with fecal microbiota was used to assess gut microbial responses to the artificial sweetener Acesulfame-K. The study found that gut microbes may metabolize the sweetener, potentially impairing intestinal barrier function.
Microbiome

Genomic Analysis of a Canine Leptospirosis Outbreak in Los Angeles County, 2021

WGS proves to be a useful tool in understanding US Canine Leptospirosis Outbreak

Leptospira Whole Genome Sequencing

08 Jun 2026 Lora Benoit Ph.D

Clinical investigation and WGS of canine Leptospira interrogans isolates from a 2021 Los Angeles County outbreak identified multiple closely related strains and demonstrated the value of applying genomic epidemiology for characterizing leptospirosis transmission in companion animals.
Clinical & Veterinary

Journal Club - 20 May to 28 May

Journal Club

Metagenomics Microbial Source Tracking Parasitology

02 Jun 2026 Lora Benoit Ph.D

Latest from our Journal Club: a rapid assay for parasite detection in game and processed meats, the TRACS platform for tracking transmission across multi-kingdom metagenomic data, and benchmarking studies defining the limits of shallow shotgun metagenomics.
Food & Beverage Microbiome Assay Development

Rapid Suspension-based Assay For Parasites in Game and Processed Meats

Detection of Meat Borne Parasites

Parasitology Trichinella spiralis

28 May 2026 Lora Benoit Ph.D

New study describes a rapid, low-cost suspension-based screening method for simultaneous detection of Trichinella, Alaria alata, and Sarcocystis spp. in raw, minced, and processed meat products.
Food & Beverage

TRACS Platform Enables Transmission Tracking Across Multi-Kingdom Metagenomic Data

New computational framework for strain-level transmission inference

Metagenomics Microbial Source Tracking

28 May 2026 Lora Benoit Ph.D

This study describes TRACS (Transmission Reconstruction Across Community Samples), a computational framework designed to infer strain-level microbial transmission directly from metagenomic sequencing data across bacteria, fungi, viruses, and bacteriophages.
Microbiome Assay Development

Benchmarking Shotgun Metagenomic Sequencing Depth Defines Limits of Shallow Metagenomics

Systematic analysis of shotgun sequencing depth for microbiome studies

Microbiome Whole Genome Sequencing

28 May 2026 Lora Benoit Ph.D

This study systematically evaluates how shotgun sequencing depth impacts taxonomic, functional, and strain-level inference in metagenomic datasets, defining practical thresholds for shallow metagenomics and highlighting limitations in de novo strain reconstruction from metagenome-assembled genomes.
Microbiome

Candida auris: High-Resolution Detection of Healthcare Transmission Using WGS

Candida auris Detection and Antifungal Resistance Using WGS

Antibiotic Resistance Candida auris Whole Genome Sequencing

20 May 2026 Lora Benoit Ph.D

A new study uses WGS to define healthcare-associated transmission clusters of Candida auris and identify antifungal resistance determinants. SNP-based thresholds combined with epidemiologic data enable accurate outbreak reconstruction and prediction of resistance-associated mutations.
Clinical & Veterinary

New Proficiency Testing Platform Enables Standardized QC for Advanced Therapy Medicinal Products

New Proficiency Testing Platform for QC of Advanced Therapy Medicinal Products

Assay Validation ATMP - Advanced Therapeutic Medicinal Products Cell and Gene Therapies

20 May 2026 Lora Benoit Ph.D

This study describes a proficiency testing (PT) and digital coordination platform designed to harmonize analytical performance across laboratories involved in Advanced Therapy Medicinal Products (ATMPs) manufacturing and Quality Control (QC).
Pharmaceutical Assay Development

Journal Club - 13 May to 18 May

Journal Club

Antimicrobial Resistance (AMR)Carbapenemase-Resistant Enterobacterales (CRE)Hantavirus

18 May 2026 Lora Benoit Ph.D

Latest from our Journal Club: understanding hantavirus, why wastewater has a role in antimicrobial resistance, how synthetic biology is reshaping gut microbiome research, and mechanisms of the spread of carbapenem resistance in enterobacterales.
Water Clinical & Veterinary Microbiome

Hantavirus - What Do You Need to Know?

Key Information on Hantavirus Infections

Hantavirus

13 May 2026 Lora Benoit Ph.D

This review of six publications on Hantavirus delivers key information points all healthcare professionals should know. Current concern centers on a cruise-associated cluster of Andes virus infections, a rare Hantavirus uniquely capable of person-to-person transmission and severe disease.
Clinical & Veterinary

Wastewater Residuals as Ecological Amplifiers of Antibiotic Resistance Genes

Dispersal of antibiotic resistance genes in the environment via treated wastewater and biosolids

Antibiotic Resistance Antibiotic Stewardship

13 May 2026 Lora Benoit Ph.D

A greenhouse mesocosm study found that wastewater residuals can promote the persistence and spread of antibiotic resistance genes (ARGs) through soil, water, plants, and earthworms, highlighting wastewater reuse in the dissemination of antimicrobial resistance in the environment.
Water

Engineering the Gut Microbiome

Synthetic biology approaches for microbiome engineering

CRISPR Microbiome Precision Medicine

13 May 2026 Lora Benoit Ph.D

This 2026 review explores the ways in which synthetic biology is reshaping gut microbiome research, enabling the rational design of engineered commensal bacteria, synthetic gene circuits, and microbial consortia for therapeutic and diagnostic applications.
Microbiome

Mechanisms of Carbapenem Resistance Spread in Enterobacterales

Mechanisms of Carbapenem Resistance in Enterobacterales

Antibiotic Resistance Antibiotic Stewardship Carbapenemase-Resistant Enterobacterales (CRE)

13 May 2026 Lora Benoit Ph.D

This 2026 review synthesizes current knowledge on the molecular epidemiology and transmission dynamics of blaNDM-5-harboring IncX3 plasmids, a key driver of Carbapenem-resistance in Enterobacterales (CRE).
Clinical & Veterinary

Comparison of 3 Commercial AST Testing of Burkholderia cepacia Complex

Comparative analysis of 3 commercial AST for B cepacia Complex

Antibiotic Sensitivity Burkholderia cepacia complex (BCC)

08 May 2026 Lora Benoit Ph.D

Study compares 3 clinical antimicrobial susceptibility testing (AST) systems - Vitek 2, Sensititre, and Etest, against reference broth microdilution (rBMD) method for Burkholderia cepacia complex (BCC), identifying substantial inter-platform variability across methods.
Clinical & Veterinary

AI-Enhanced Biosensors Improve Pathogen Detection in Complex Food Matrices

AI Enhanced Biosensors for Pathogen Detection in Complex Food Matrices

Artifical Intelligence Listeria spp.Salmonella

08 May 2026 Lora Benoit Ph.D

AI-integrated biosensors combine advanced biorecognition and machine learning to reduce matrix interference, improve signal interpretation, and enable rapid detection of pathogens in complex food systems.
Food & Beverage

Rapid Detection of Salmonella using a RPA–CRISPR/Cas12a Platform

Salmonella enterica detection using a RPA CRISPRCas12a Platform

CRISPR LAMP/Isothermal Amplification Salmonella

07 May 2026 Lora Benoit Ph.D

Novel diagnostic system for rapid detection of Salmonella enterica that combines isothermal nucleic acid amplification with CRISPR-based collateral cleavage to enable highly sensitive and specific detection.
Food & Beverage Clinical & Veterinary Assay Development

Journal Club - 27 April to 12 May 2026

Journal Club

Antibiotic Sensitivity Artifical Intelligence Burkholderia cepacia complex (BCC)

12 May 2026 Lora Benoit Ph.D

Latest from our Journal Club: Variability in AST systems for Burkholderia cepacia complex, AI-integrated biosensors for rapid pathogen detection in complex food systems, CRISPR-based diagnostic platform enabling rapid, sensitive detection of Salmonella enterica.
Food & Beverage Clinical & Veterinary Assay Development

Journal Club - 26 April to 5 May 2026

Journal Club

Blood Culture Candida auris Hospital Acquired Infection (HAI)

05 May 2026 Lora Benoit Ph.D

Latest from our Journal Club: Polymicrobial Dysbiosis drives Noma, Yeast ID methods, antifungal susceptibility testing (AST) practices, and C. auris screening, and Rapid, accurate sepsis diagnostics, using the Molecular Mouse.
Clinical & Veterinary Microbiome

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MinION portable sequencer from Oxford Nanopore Technologies

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Sterility testing in 5 hours not 14 days

advertisement

Neogen Webinar on LAMP Technology in Food Safety Testing

advertisement

understanding gluten

advertisement

This site is a B2B information site for professional use - clinical diagnostics products listed are for Research Use Only unless otherwise stated.

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