Summary: Latest from our Journal Club: Polymicrobial Dysbiosis drives Noma, Yeast ID methods, antifungal susceptibility testing (AST) practices, and C. auris screening, and Rapid, accurate sepsis diagnostics, using the Molecular Mouse.
Shotgun metagenomic sequencing of oral samples from children with noma revealed a distinct polymicrobial dysbiosis, characterized by enrichment of anaerobic and opportunistic pathogens, supporting a community-driven disease model.
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This survey-based study evaluated yeast identification methods, antifungal susceptibility testing (AST) practices, and C. auris screening strategies across US hospitals.
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Using the Molecular Mouse (MM) Sepsis panels (Alifax, Padova, Italy), 144 residual positive blood culture samples from non-replicated patients were analysed, comparisons were made with a typical methodology that includes cultures, MALDI-TOF MS, AST, and RT-PCR.
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This week's Journal Club Explores: How Polymicrobial Dysbiosis drives noma, Yeast ID methods, antifungal susceptibility testing (AST) practices, and C. auris screening, and the ongoing transition of blood culture diagnostics toward rapid molecular syndromic testing integrated with antimicrobial resistance profiling, as the Molecular Mouse (MM) Sepsis panels were analysed and showed accuracy.
