Omicron spike proteins and antibodies now available

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30th November 2021 Product update: rapidmicrobiology.com

Special Focus on Molecular Testing for SARS-CoV-2 (COVID-19) Variants Including Omicron

Recombinant Omicron Variants are Available

The latest SARS-CoV-2 variant of concern, named Omicron, has approximately 30 spike protein mutations, almost double its predecessor Delta. It also has a mutation that the alpha variant possesses, which is picked up as S-gene failure on RT-PCR tests. That gives it the ability to evade our antibody responses, which is one of the reasons it has been classified as a VOC. The variant has spread rapidly in South Africa, from being first detected in early November to now being detected in 90% of positive SARS-CoV-2 samples.

Vaccine manufacturers are now assessing if current shots effectively prevent the severe disease from the variant, and Moderna has released a statement to say they will have tweaked their vaccine in early 2022 to protect against Omicron.

The emergency brake hasn't been pulled yet, allowing the variant to spread to all communities, and with flu season still down the line, PCR testing labs and suppliers will be put under serious pressure in the coming weeks. Read this updated version of our variant special and contact a test kit provider today.

Sino Biological Deposits Recombinant Omicron Proteins and Antibodies to BEI Resources

Sino Biological, Inc. has deposited reagents for the Omicron variant, including recombinant proteins to Spike and Nucleocapsid, and antibody products to BEI Resources, a central repository for reagents to support infectious disease research.
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Recombinant SARS-CoV-2 Omicron Variant (B.1.1.529) Protein

Creative Diagnostics has launched Recombinant SARS-CoV-2 Omicron Variant (B.1.1.529) Protein for the research uses, such as Recombinant SARS-CoV-2 (COVID-19) Spike Protein NTD (B.1.1.529) [His] (DAG-WT549).
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SARS-CoV-2 Omicron Spike Proteins and Antibodies Available

The nucleocapsid protein is commonly used as the biomarker in rapid antigen tests. It’s critical to assess whether the current commercial antigen tests can detect the mutated N proteins with the same sensitivity and specificity as their WT counterpart.
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Specific PCR-based Detection of SARS-CoV-2 Including New Variants

The EURORealTime SARS-CoV-2 provides fast and highly specific detection of SARS-CoV-2 including the variants alpha (B.1.1.7), beta (B.1.351), gamma (P.1), delta (B1.617.2), lambda (C.37), mu (B.1.621) and omicron (B.1.1.529).
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Panel of Research Reagents for SARS-CoV-2 Omicron Variant (B.1.1.529) Launched

Sino Biological, Inc. has launched a panel of research reagents for the newly identified Omicron which has quickly raised concerns around the world because of the high number of mutations it carries, especially the 30-plus mutations on the Spike protein.
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A Move to a Nanolitre-Based Platform Can Reduce SARS-CoV-2 Reagent Use and Hands-on Time

Labs can save reagents and hands-on time using Fluidigm's new 'Custom Targeted-Sequencing Assay Pool Set for the SARS-CoV-2 Genome'. In this interview with Roberto Spada (Fluidigm), he explains how this is possible with the Juno™ bench-top system and the essential data it provides.
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PCR Products You Can Rely On – Expanded Range from PCR Biosystems

PCR Biosystems is committed to providing researchers, developers, and diagnostics manufacturers with the PCR products they need in the global response to COVID-19. Discover how to boost the accuracy and sensitivity of SARS-CoV-2 detection.
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Skip Extraction of SARS-CoV-2 with MicroLYSIS-RNA

MicroLYSIS RNA is a powerful reagent for COVID-19 testing by releasing RT-qPCR-ready RNA from a range of samples that include: swabs, viral transport medium, and saliva. The resulting lysate is ready for RT-qPCR testing.
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B.1.1.7, B.1.351, & P-1 Inactivated Whole Virus SARS-CoV-2 Variants

Microbiologics offers high titer inactivated whole virus RUO materials for B.1.1.7, B.1.351, and other SARS-CoV-2 variants.
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Reagent Resource for Studying SARS-CoV-2 Variants

Sino Biological has developed 80+ recombinant RBD/Spike, and N protein mutants carrying the mutations of high interest, such as N501Y and E484K identified in three fast-spreading SARS-CoV-2 variants, U.K. B.1.1.7, Brazil P.1, and South Africa B.1.351.
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