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10th March 2020  Content supplied by: rapidmicrobiology.com

Special Focus on Endotoxin / Pyrogen Testing

Browse through our rapidmicrobiology special focus on tests for endotoxins and Non-Endotoxin Pyrogens (NEP), learn from leading experts in the field such as Allen Burgenson who gives us the latest on how use of recombinant Factor C (rFC) is gaining pharmacopeial acceptance for compendial Bacterial Endotoxin Testing (BET); Kevin Williams describes how the use of pre-spiked plates can improve efficiency and give a rapid result; plus find out how the Monocyte Activation Test solution better represents the human immune response and will detect all pyrogens including NEPs such as from yeasts/molds and viruses.

Once you've read through all these, you'll be ready to take our pyrogen and endotoxin testing quiz - check to see if you really know the difference between LAL, rFC, MAT!

The Compendia Are Ready to Adopt rFC, Are You?​

Lonza Pyrogene

In this article, Allen L. Burgenson, Global Subject Matter Expert, Lonza Pharma&Biotech – Testing Solutions, reviews how leading pharmacopeias are moving towards acceptance of the use of recombinant Factor C (rFC) for compendial Bacterial Endotoxin Testing (BET).

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The Most Expensive Test Is the One You Have to Do Twice. 

Charles River Endotoxin Testing Solutions

Charles River’s portfolio of FDA-licensed products for bacterial endotoxin testing is designed to increase data integrity compliance, reduce retest rates, and streamline manufacturing processes, allowing prompt, confident decisions.

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PyroMAT® System, a Suitable Solution for the Detection of a Wide Range of Pyrogens

Monocyte Activation Test

The PyroMAT® system is a Monocyte Activation Test solution that uses a monocytic cell line for the detection of pyrogens. It has been demonstrated that this cell line can detect a wide range of pyrogens by using several TLR ligands.

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Increasing Efficiency in Endotoxin Testing​


Endotoxin Testing can be difficult, time-consuming and associated with multiple re-testing. With new technologies in the market, increasing efficiency in your testing solutions can be easily and “rapidly” implemented. Kevin L. Williams, Microbiological Test Development, bioMérieux, explains.

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Prerecorded free to view webinars:

Merck Millipore - In Vitro Pyrogen Detection: the New Trend

bioMerieux - Low endotoxin recovery: assessment of PDA technical report no.82 and demasking of endotoxin with dedicated sample treatment

QC Insider Toolbox - Endotoxin Expertise at Your Fingertips - Lonza's QC Insider™ Toolbox is packed with comprehensive support tools that will help you perform the bacterial endotoxins test.   



Date Published: 10th March 2020

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