In recent years the LAL test has become the preferred system to test for endotoxins, both for in-process control as well as for final inspection, and it is anchored in the pharmacopoeias.  However, the problem of low endotoxin recovery is a challenge for the pharmaceutical microbiologist.  Masking – or not?  Evidence gaps?  And how to close them?  How to evaluate?

Join ECA Academy for this hands-on laboratory-based training and learn from experts in the field of Endotoxin testing.

Objectives

• How to identify Low Endotoxin Recovery (LER)
• How to Set-up hold-time studies
• Analysis of influencing factors (Sample matrices, endotoxin, temperature, detection methods, etc.)
• Understanding the driving forces of LER
• Interpretation of test results
• Dedicated sample treatment for demasking