This cell line is constructed by transduction of human angiotensin I converting enzyme 2 (ACE2) into HEK293T cells, followed by stable cell selection. HEK293T is derived from HEK293 and is commonly used in scientific research. HEK293T-human ACE2 cell line can be used for in vitro screening and characterization
Pseudotyped Luciferase/GFP rSARS-CoV-2 Spike is used to test the ability of serum, antibodies, and drugs to neutralize the infectivity of SARS-CoV2 spike protein. Pseudovirus display an antigenically-correct spike protein pseudotyped on replication-incompetent virus particles that contain a heterologous lentiviral (HIV) core.
Pseudotyped Luciferase/GFP rSARS-CoV-2 Spike is capable of