LAL is a vital protein coagulation system found in horseshoe crab blood that is capable of detecting harmful endotoxins found on the outer membrane of Gram-negative bacteria.

The past year was highly eventful for the horseshoe crab (HSC) and their stakeholders. The Atlantic States Marine Fisheries Commission (ASMFC) completed a comprehensive two-year study on the status of the American HSC and found that its population was either stable or flourishing throughout the Atlantic coastal waters and that the Limulus amebocyte lysate (LAL) industry had no negative impact on HSC or migratory bird sustainability.^[1]

In this article authored by Dr. James Cooper PHARMD marine scientists document the LAL industry's conservation of the horseshoe crab.  Click here to read the article in full.

^[1] Atlantic States Marine Fisheries Commission 2019 Horseshoe Crab Benchmark Stock Assessment and Peer Review Report