Aalto Bio Reagents Ltd. has announced the availability of its new peptides for Monkeypox virus (MPV) B21R- and B21R-B - BSA conjugate.

MPV belongs to the Orthopoxvirus genus of the Poxviridae family, which is the same genus as the variola virus (the cause of smallpox). Orthopoxviruses have highly conserved genomes, which can lead to significant antibody cross-reactivity among its members. The development of a standard antibody test for MPV is complicated by cross-reactive immune responses induced by vaccina, the virus used in smallpox vaccines.

Aalto Bio’s new MPV peptides contain the surface glycoprotein B21R and this region contains important antibody targets as well as several key immunodominant epitopes. When conjugated to a carrier protein like BSA, this has been shown to greatly improve the sensitivity of the assay compared to unconjugated peptide, and enhance stability.

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