FUJIFILM Wako Chemicals U S A Corporation

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5th September 2023  Content supplied by: FUJIFILM Wako Chemicals U.S.A. Corporation

Pyrostar™ NEO, an Endotoxin Detection Reagent Developed by Recombinant Technology

PYROSTAR™ Neo is a new synthetic endotoxin-detection reagent that combines 3 recombinant factors (factor C, factor B, proclotting enzyme), with DNA sequences derived from Limulus polyphemus and a chromogenic substrate (peptidyl pNA), to closely mimic the cascade pathway of traditional LAL. This highly sensitive and specific assay is a fully sustainable product that reduces the burden on the natural environment while supporting a more consistent testing process.


  • Colorimetric method that can be used with an absorbance plate reader.
  • 3-Factor system mimics the same cascade reaction as traditional LAL
  • Endotoxin-specific reagent eliminates the risk of false positives from (1-->3)ß-D-Glucan
  • 100% synthetic with no utilization of horseshoe crab blood
  • Quantitative range: 0.001 to 50EU/mL
  • High sensitivity with less lot-to-lot variation
  • Stable storage after dissolution (4 hrs. at 2-8°C and 2 weeks at -30°C
  • Validation data available from the manufacturer

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Date Published: 5th September 2023

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FUJIFILM Wako Chemicals U.S.A. Corporation


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