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17th July 2014  Content supplied by: ATCC

Establishing Limit of Detection with Quantified ATCC Strains and Nucleic Acids

The performance of culture- and molecular-based assays is often evaluated through the examination of sensitivity, specificity, and limit of detection (LOD). Depending on the assay, LOD is the minimum amount of target microorganisms or genome copies that can be reliably detected under optimal conditions. Accurate determination of LOD relies on the use of authenticated microbial or molecular controls with known concentrations.

For this reason, ATCC has expanded its portfolio of products and services to include:

  • Quantified microorganisms
  • Native nucleic acids with known concentration
  • Synthetic nucleic acids with calculated genome copy number
  • Extraction and quantification services

These products are produced under ISO 9001:2008 certified and ISO/IEC 17025:2005 accredited processes, and are quantified using verified methods, so you can trust the accuracy of your results.

To learn more about how ATCC can help you establish assay sensitivity, visit us online at  Or, contact the ATCC Sales Team.

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Date Published: 17th July 2014

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