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Update of USP Drug Testing Reference Strain ATCC® 2601™

ATCC® No. 2601™, designated as a reference strain by the FDA, is widely used in amphotericin B (Fungizone®) and nystatin (fungicidin) quality control assays in accordance with the U.S. Pharmacopeia General Chapters: <81> ANTIBIOTICS-MICROBIAL ASSAYS (USP35-NF30 2012). Its designation as Saccharomyces cerevisiae is based on traditional taxonomic characterizations. However, questions regarding the taxonomic identity of ATCC® No. 2601™ have motivated us to perform a polyphasic study to clarify its true taxonomic identity and phylogenetic position. The results from our multi-gene sequence analysis indicate that this strain is clearly distinguishable from typical S. cerevisiae strains and that it belongs to the species Saccharomyces kudriavzevii, a close relative of S. cerevisiae. Therefore, we proposed that ATCC® No. 2601™ be renamed S. kudriavzevii to reflect its true identity. The updated name of this organism will not affect its application in antifungal drug testing assays.

Learn more about ATCC Quality Control Strains.

NOTE: This item is from our 'historic' database and may contain information which is not up to date.

Source: ATCC View latest company information

Posted: October 22, 2012
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