Thermo Fisher Scientific Introduces Medium for Faster Screening of CRE, Including NDM-1

Thermo Fisher Scientific has launched Thermo Scientific Brilliance™ CRE Agar, a medium for faster and easier detection of carbapenem-resistant Enterobacteriaceae (CRE). It is recognized that the only way to stop the spread of infections by resistant bacteria, such as CRE, is to rapidly identify and isolate any hospital patients who are infected with the resistant strain1. Laboratories can use Brilliance CRE Agar to screen patient samples for CRE and provide clinicians with results in just 18-24 hours. This faster time to result accelerates the start of infection control measures, including accurate antibiotic prescription, for better patient outcomes.
Brilliance CRE Agar is easier to use and read than the Hodge test traditionally used to detect resistance to carbapenems. Brilliance CRE Agar contains a modified carbapenem, at levels recommended by both the CLSI and EUCAST, ensuring reliable detection of numerous CRE strains, including those with the NDM-1 mechanism of resistance2. Chromogenic compounds in the medium differentiate between resistant E. coli (pink colonies) and Klebsiella, Enterobacter, Serratia or Citrobacter (KESC) organisms (blue colonies). The colonies of other resistant organisms appear white and are easy to spot against the novel pigmented agar.

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1. BBC News, 11 August 2010. New Superbug found in UK hospitals.
2. Kumarasamy KK, Toleman MA, Walsh TR (2010) Emergence of a new antibiotic resistance mechanism in India, Pakistan, and the UK: a molecular, biological, and epidemiological study. The Lancet Infectious Diseases 10(9): 597 - 602

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Posted on July 5, 2011