Principle: Interferon-gamma release assay (IGRA)
Suitability: Supports detection of past contact with SARS-CoV-2 or detection of an immune response following vaccination against the virus
Capital equipment required: NO
The Quan T-Cell ELISA used in combination with the Quan-T-Cell SARS-CoV-2 is an interferon-gamma release assay (IGRA) for quantitative determination of the IFN-γ release of SARS-CoV-2-specific T cells.
- Use of heparinised whole blood samples – no preparation of purified peripheral mononuclear cells (PBMCs) required
- T-cell stimulation based on the highly immunogenic SARS-CoV-2 spike protein and subsequent determination of released IFN-γ by means of a fully automated quantitative ELISA