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Rapid ID of Nosocomial Infections - GENSPEED® MRSA and C. Diff OneStep

Greiner Bio-One has developed the GENSPEED® Test System, a unique molecular diagnostics system that combines crude lysis of bacteria with multiplex-PCR before the final automated analysis of PCR-products in the new GENSPEED® R2 device.

For rapid detection of MRSA, the GENSPEED® MRSA Test running on the GENSPEED® Test System was developed. It is a DNA-based in-vitro diagnostic tool for qualitative detection of MRSA within 75 minutes from human nasal and pharyngeal smears, targeting both resistance genes mecA and mecC.

With the GENSPEED® C.Diff OneStep, toxigenic C. difficile can be rapidly identified by detecting genes for glutamate dehydrogenase (GDH), toxin A, toxin B and binary toxin in one step in less than 90 minutes. With this one-step procedure GENSPEED® C.Diff OneStep clearly outdates the sequential diagnostic procedure (two-step method according to ESCMID-guidelines) that uses at least two different test systems, e.g. a GDH antigen assay followed by a toxin assay. GENSPEED® C.Diff OneStep will be launched by the end of this year.

The GENSPEED® Test System in general scores points for speed and high sensitivity at a reasonable price. Analyses of individual samples are possible at any time. Three controls (for DNA amplification, hybridization, as well as a negative control) on the Test Chip offer great reliability. The compact and maintenance free system was designed for optimal ease of use. Pre-filled reagents and the automated GENSPEED® R2 device reduce the number of process steps to a minimum. GENSPEED® is an inexpensive solution that is already available on the market.

Tags: Clostridium difficile, MRSA, Multi-Drug Resistant Organisms

Date Published: November 17, 2014

Source article link: Greiner Bio-One GmbH » company contact details
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