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16th August 2020  Product update: Paul Carton

China-US Government Program Assess Gastrointestinal Pathogen Detection Panels

A study comparing the performance of two well-known gastrointestinal pathogen detection panels has been carried out by the China-US Collaborative Program on Emerging and Re-Emerging Infectious Diseases.

The Luminex xTAG Gastrointestinal Pathogen Panel (GPP) and bioMérieux’s BIOFIRE® FilmArray® Gastrointestinal Panel were evaluated on their ability to detect norovirus, rotavirus and Campylobacter, Cryptosporidium, Salmonella, Shiga-Toxin e. coli (STEC) and Enterotoxigenic e. coli.

The study showed positive rates of 65% and 48.6% for FilmArray and xTAG GPP respectively. Both panels were able to detect norovirus, rotavirus, and Campylobacter, but had low consistency in detecting CryptosporidiumSalmonella, Shiga toxin-producing Escherichia coli (STEC) and enterotoxigenic E. coli (ETEC).

FilmArray outperformed the xTAG GPP in detecting low concentration targets in the study, and xTAG GPP was more likely to be affected by amplification inhibitors and had problems detecting ETEC.



Date Published: 16th August 2020

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Note: This content has been edited by a rapidmicrobiology staff writer for style and content.